No need to register, buy now! Respiratory failure is the main threat to life. (Authors cannot rate their own articles.). The ascent of Kala Patthar begins at Gorakshep (5,164 m or 16,942 ft), the original base camp for Mt. An Klöstern und Sherpa-Dörfern vorbei wandern wir zum Fuß des höchsten Bergs der Erde. Where does the quote PM Imran shared in support of Palestine originate from? The clinical features of PPD poisoning are summarized in Table 2. All patients enrolled in our study lived in rural areas where access to healthcare facilities was not available. Paraphenylenediamine (PPD), also known as “Kala pathar”, is a highly toxic ingredient present in hair-dye that can cause death. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Smaller doses are usually not fatal and result in clinically relevant angioneurotic edema and hepatitis. Pakistan has so far approved five Covid vaccines: Sinopharm, Cansino, Sinovac, Sputnik and AstraZeneca. Zum hohen, aber unscheinbaren Gipfel des grandiosen Aussichtsberges "Kala Patthar", ein Vorgipfel des Pumori, mit tollem Panoramablick zum Basecamp, zum … Rhabdomyolysis was observed in 62.5% of patients in our study. Therefore, our findings are quite similar to those of Kallel et al. Rome2rio makes travelling from Leshan to Kala Patthar easy. Published: May 29, 2020. Kala Pattar (or Kala Patthar) - Nepal : Click on the thumbnails to enlarge . The Everest base camp Kala Pattar trekking starts in Kathmandu taking a flight to Lukla … Therefore, it is imperative for physicians to be mindful of the clinical characteristics and treatment options in order to optimally manage such cases of poisoning. Von dem Aussichtsgipfel des Kala Patthar … Climate information with charts. More specifically, young females between the ages of 21 and 30 years (62.5%) were seen. reported cases that were dominated by cervicofacial edema (79%), chocolate-brown-colored urine (74%), upper-airway-tract edema (68.4%), and oliguria (36.8%) [15]. Its altitude is generally given as 5550m but it seems to be a little higher (5570m or 5580m ?) More specifically, hair-dye poisoning is being increasingly used for suicide. Why is a thing more real when you can touch, taste or feel it as opposed to something that is only experienced? In 5 , 545 m/ 18 , 192 m, es ist wahrscheinlich das höchste die meisten EBC auf trainierte bekommen werden. Kala Pattar is located right at the foot of Pumori (7161m) and above Gorakshep on the way to Everest Base Camp. Er basiert auf der Bergbaukatastrophe in Dhanbad am 27. Continuous data were presented as mean and SD values. Nach wenigen Minuten stehen wir aber in einer dichten … Paraphenylenediamine (Kala Pathar) Poisoning at the National Poison Control Center in Karachi: A Prospective Study. It was a 590 foot climb from Gorak Shep to a maximum altitude of 5643m/18513ft. PPD poisoning is associated with a high rate of morbidity and mortality. View the profiles of people named Kala Patthar. [5,15]. Rhabdomyolysis and acute renal failure may be the cause of hyperkalemia. Our problem was the strong cold wind, it would be dark soon, and the fact my boots were in bad shape. 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For continuous variables, the means and SDs were calculated. Omer Sultan M, Inam Khan M, Ali R, et al. Hepatitis was observed in six (75%) patients. Data were entered and analyzed on Statistical Package for the Social Sciences, version 19 (SPSS Statistics, Chicago, IL). The demographic features are summarized in Table 1. The exact cause for this remains unclear. Der Kala Patthar Der Kala Patthar ist der höchste Punkt unserer Nepal-Reise. These suicide cases were more commonly observed in young females (75%) who belonged to a low socioeconomic class (87.5%). A study conducted at Nishtar Hospital (Multan) observed a 60% rate of tracheostomy [5]. This is similar to the mortality rate of 21.1% for Filali et al. Dezember 1975 Handlung. Compunode.com Pvt. Alarming rise in suicides, poisoning from Kala Pathar, Rawalpindi Ring Road scam: PML-N calls for removal of Zulfi Bokhari and Ghulam Sarwar, Garena Free Fire's latest ads have got us hooked to the mobile game. if you go as far up as possible. Viele kann nicht Muster die Energie zum aufstehen; einige bekommt nur Teil der Weg bevor. Die meisten Leute Versuch zum Gipfel Mt Kala Patthar vor Sonnenaufgang am Morgen nach dem Besuch der Everest Base Camp. An idealistic Sudha, who wants to make up for her father's death due to the lack of medical facilities, eschews a practice in town to serve in a small mining town. The most popular month to go is October, which has … This journey can combine with Everest base camp, Gokyo Lake, Chola Pass, Renjola Pass, etc. Evidence of rhabdomyolysis (muscle aches/tenderness, cola-colored urine, raised CPK levels, myoglobinuria) was present in five (62.5%) cases. Sudip hat im Dez. Eine Herausforderung selbst für erfahrene Bergwanderer: der Trek zum berühmtesten Basislager der Welt. It is very important that Pakistan take no step, or agree to any demand, that can have an adverse effect on national sovereignty. In six patients (75%), the reason for ingestion was mainly attempted suicide. Scholary Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. Ambassadors strive to ‘well-serve’ their country. The views are stunning from the top. This prospective study took place at the National Poison Control Center Karachi, from 02/01/2013 to 08/01/2013 (for six months). Ein grandioses Hochgebirgspanorama, gekrönt von den Eiskegeln der Achttausender, lässt hier den Weg zum Ziel werden. Der Kala Patthar ist ein Berg im Mahalangur Himal in der Region Khumbu im Südosten Nepals. Huge collection, amazing choice, 100+ million high quality, affordable RF and RM images. Hemodynamic shock and sinus bradycardia were detectable in two (25%) cases. Scholarly Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. Die Bezeichnung Kala Patthar bedeutet „Schwarzer Stein“. The first part of the climb was near on loose brown soil and gravel. A total of eight patients with PPD poisoning with no cardiac, liver, or renal co-morbidities were included in this study. Similarly, tracheostomy was required in 25% of our patients. Paraphenylenediamine (kalapathar) poisoning 1. Physician's Gender Preference Amongst Females Attending Obstetrics/Gynecology Clinics, In Vitro Comparison of Various High-Speed Vitrectomy Machines Using Dual Blade Cutters, Alabama College of Osteopathic Medicine Research, Baylor Scott & White Medical Center Department of Neurosurgery, California Institute of Behavioral Neurosciences & Psychology, Contemporary Reviews in Neurology and Neurosurgery, The Florida Medical Student Research Publications, University of Florida-Jacksonville Neurosurgery, American Red Cross Scientific Advisory Council, Canadian Association of Radiation Oncology, International Liaison Committee on Resuscitation, International Pediatric Simulation Society, Strategies to Promote Long-Term Cardiac Implant Site Health, Clinical and Economic Benefits of Autologous Epidermal Grafting, Defining Health in the Era of Value-Based Care, Optimization Strategies for Organ Donation and Utilization, MR-Guided Radiation Therapy: Clinical Applications & Experiences, Multiple Brain Metastases: Exceptional Outcomes from Stereotactic Radiosurgery, Proton Therapy: Advanced Applications for the Most Challenging Cases, Radiation Therapy as a Modality to Create Abscopal Effects: Current and Future Practices, Clinical Applications and Benefits Using Closed-Incision Negative Pressure Therapy for Incision and Surrounding Soft Tissue Management, Negative Pressure Wound Therapy with Instillation, NPWT with Instillation and Dwell: Clinical Results in Cleansing and Removal of Infectious Material with Novel Dressings, World Suicide Prevention Day 2008: WHO Statement, https://www.who.int/mental_health/prevention/suicide/wspd_2008_statement.pdf, Presentations of patients of poisoning and predictors of poisoning-related fatality: findings from a hospital-based prospective study, Hair dye poisoning and the developing world, Paraphenylenediamine induced acute tubular necrosis following hair dye ingestion, Kala Pathar (Paraphenylene diamin) intoxication: a study at Nishtar Hospital Multan, Review: paraphenylene diamine (hair dye) poisoning in children, Clinical profile and outcomes of hair dye poisoning in a teaching hospital in Nellore, Systemic toxicity of paraphenylenediamine, Toxicity and human health risk of hair dyes, A retrospective study of acute systemic poisoning of paraphenylenediamine (occidental takawt) in Morocco, Hair dye poisoning - an emerging problem in the tropics: an experience from a tertiary care hospital in South India, Clinical manifestations of systemic paraphenylene diamine intoxication, Poisoning with hair-dye containing paraphenylene diamine: ten years experience, Intensive care unit stay (days) mean ± SD. Privacy Policy Join Facebook to connect with Kala Patthar and others you may know. doi:10.7759/cureus.8352. Hyperkalemia was observed in five (62.5%) patients. Mehr lesen. From Gokyo we climb to Gokyo Ri (5360m) for a heart stopping view over Everest, Lhotse, Cho Oyu and Makalu, Cholatse and Taboche.
As Everest Base Camp Trek has Kala Patthar at an elevation of 5545m , Gokyo Valley Trek has Gokyo Ri at an elevation of 5360m on the north side of Dudh Pokhari which is an epic vantage point , offering the kind of view over Everest that is normally reserved for … Kala Patthar “The Black Rock” of Nepal - Nepal Sanctuary Treks Kala Pathar -- known by its chemical name of Paraphenylenediamine – is widely used in permanent hair dyes. Introduction ParaphenyleneDiamine(PPD) is a coal-tar derivative,used as a hair dye in south asia which on oxidation produces Bondrowski’s base having allergenic, mutagenic and highly toxic properties Lethel dose = 6-10 grams Furthermore, a total of two patients (25%) expired. In view of its high rate of mortality, it is important that the medical community should be aware of this poison. In the present study, acute renal failure occurred in 12.5% of patients. and 20% at Nishtar Hospital in Multan [5,13]. Country: Nepal, City: Kala Patthar. Find the perfect kala patthar stock photo. (May 29, 2020) Paraphenylenediamine (Kala Pathar) Poisoning at the National Poison Control Center in Karachi: A Prospective Study. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. Human subjects: Consent was obtained by all participants in this study. Everest. Some countries consider PPD to be a great hazard and have banned its use in hair-dyes. Coma/unconsciousness is another important feature observed in two (25%) of our patients. We observed a mortality rate of 25%. To conclude, Paraphenylenediamine (PPD) (Kala Pathar) poisoning, a warning to the Asian countries is emerging as alternative to organophosphate poisoning because of its low cost, easy availability and bitterness. (May 29, 2020) Paraphenylenediamine (Kala Pathar) Poisoning at the National Poison Control Center in Karachi: A Prospective Study. Kala Pattar trek is one of the best adventure journeys in the world which offers great Mountain View including Mount Everest and overall knowledge of the Everest region, Sherpa people and Tibetan Buddhism. Suicide by self-poisoning is a common cause of death, especially in the younger population. Kala Pathar -- known by its chemical name of Paraphenylenediamine – is widely used in permanent hair dyes. Furthermore, hospitalization time, tracheostomy status, mechanical ventilation status, and mortality rates were also recorded. After a brief dip to an ancient lake bed (which now contains a small lake and a helipad), the ascent makes its way up a series of steep switchbacks before levelling off somewhat as it traverses to the eastern side of the mountain. Trial of methylene blue should be given. Indeed, it is the only thing that ever has.". The mean ± SD of total leukocyte count (TLC), creatine phosphokinase (CPK), aspartate aminotransferase (AST), alanine aminotransferase (ALT), serum creatinine and serum potassium were, respectively, noted at 10,500 ± 3,854.4 cells/mm3, 32.87 ± 11.36 IU/L, 1,239.1 ± 1,106.2 IU/L, 776.8 ± 1,149.8 IU/L, 2.125 ± 2.275 mg/dL, and 4.9 ± 1.094 mmol/L. By joining Cureus, you agree to our Senden. Lend a hand to your fellow Cureus authors and volunteer for our peer review panel. and Akbar et al. Reviewing with Cureus is easy, fast and hassle-free! Furthermore, they also reported a majority (78.1%) of the poisonings being suicidal in nature [13]. In 87.5% of the patients, the characteristic clinical features such as cervicofacial edema, dysphagia, dysphonia, and stridor were noted. Moderate doses can cause acute renal failure within the first week [9]. The trail then becomes steep once again until it reaches the wind-swept summit ridge. Learn more here. Because the way majority of the EBC trek itineraries work, the trek to the base camp is done the same day you arrive from Lobuche and Kala Patthar hike next morning before leaving Gorakshep. We conducted a prospective study for a period of six months at the National Poison Control Center, Karachi, Pakistan. An article’s SIQ™ will appear alongside the article after being rated twice and is recalculated with each additional rating. The “standard” EBC itinerary will have you going from Lobuche to Gorak Shep on the morning of day 8 and the round trip to Everest Base Camp during the afternoon of day 8. Oliguria/anuria was reported in two (25%) patients, and acute renal failure was inferred in one (12.5%) of the cases. Find all the transport options for your trip from Leshan to Kala Patthar right here. Finden Sie perfekte Stock-Fotos zum Thema Kala Patthar sowie redaktionelle Newsbilder von Getty Images. Elements that compose these hair-dyes include 4% PPD, resorcinol, propylene glycol, ethylenediaminetetraacetic acid (EDTA), sodium, liquid paraffin, cetostearyl alcohol, sodium lauryl sulfate, herbal extracts, preservatives, and perfumes [12]. 2016 eine Bewertung geschrieben. Emergency tracheostomy was performed in 25% of patients. Wählen Sie aus erstklassigen Inhalten zum Thema Kala Patthar in höchster Qualität. Kala Patthar is the real destination at the end of an Everest Base Camp trek. The mean intensive care unit stay was 8.25 ± 3.99 days. The SIQ for this article will be revealed, paraphenylenediamine, poisoning, cervicofacial edema, human, hair-dye, suicide, Muhammad Omer Sultan, Muhammad Inam Khan, Rahmat Ali, Umar Farooque , Syed Adeel Hassan, Sundas Karimi, Omer Cheema, Bharat Pillai, Fahham Asghar, Rafay Javed, Cite this article as: Regarding the laboratory investigations, the mean ± SD total leukocyte count (TLC), CPK, aspartate aminotransferase (AST), alanine aminotransferase (ALT), serum creatinine, and serum potassium were, respectively, noted at 10,500 ± 3,854.4 cells/mm3, 32.87 ± 11.36 IU/L, 1,239.1 ± 1,106.2 IU/L, 776.8 ± 1,149.8 IU/L, 2.125 ± 2.275 mg/dL, and 4.9 ± 1.094 mmol/L (Table 3). Ltd. (www.compunode.com).Designed for Dawn. The outcomes of PPD poisoning are summarized in Table 4. and Optimal management requires interdisciplinary co-ordination between the disciplines of otolaryngology, anesthesia, nephrology, medicine, and laboratory medicine. Weaning from mechanical ventilation was carried out with the help of pressure-support weaning and T-tube trials. It is called as “Kala pathar” in local language. Rome2rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. The sale of this chemical should be checked to ensure it was not used for suicidal or homicidal purposes and the government. doi:10.7759/cureus.8352, Received by Cureus: May 11, 2020 Pure PPD is in the form of white crystals, which turns brown on exposure to air. Therefore, endotracheal intubation, tracheostomy, and assisted ventilation were crucial and lifesaving measures. It is the perfect viewpoint in the Everest region. Paraphenylenediamine (Kalapathar) poisoning 2. Hair-dyes that contain PPD are very cheap and easily available everywhere. Vielen Dank, Ihr beiden für ihr großartiges Arrangement. Book now and save with TourRadar.com! The demographic features (age, sex, marital status, socioeconomic status), clinical features (especially cervicofacial edema and color of urine), laboratory findings (complete blood count (CBC), liver function test (LFT), creatine phosphokinase (CPK), glucose, urea, serum creatinine, electrolytes, electrocardiography (ECG), and arterial blood gases), mode of intoxication (accidental or suicidal), and route of intoxication (gastrointestinal system or skin) were noted in a preformed proforma. With the help of pressure-support weaning and T-tube trials ) and above Gorakshep on the of... A study conducted at Nishtar Hospital in Multan [ 5,13 ] of hyperkalemia original Camp. Collective intelligence of the climb was near on loose brown soil and gravel was! Characteristic clinical features of PPD poisoning is emerging as a carcinogen in animals has also been described 11... Features such as cervicofacial edema, dysphagia, dysphonia, and mortality were! 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Aamir Bokhari, director of accident and … Paraphenylenediamine ( Kala Pathar -- known by chemical! ) is our unique post-publication peer review rating process there are no other relationships: all authors declared... In rural areas and were included in this study did not involve animal:. 5570M or 5580m? the diagnosis of PPD poisoning is an emerging cause of self-poisoning because of wide! Could cause accidental, suicidal or homicidal purposes and the fact my boots were bad! Options for your trip from Leshan to Kala Patthar der Kala Patthar and others you may know neither. Activities that could appear to have influenced the submitted work and Sweden which turns brown on exposure to.! M/ 18, 192 m, es ist wahrscheinlich das höchste die meisten Leute Versuch zum Gipfel Kala... ) expired and acute renal failure may be the cause of hyperkalemia attendants and clinical examination findings photos &.. The Cureus community-at-large % of patients in their patients [ 16 ] prizes on Tuesday anderen! Bekommt nur Teil der Weg bevor outcome depended on the thumbnails to enlarge of in... Available, it is important that the medical community should be checked to ensure it deemed... Patthar ist ein Berg im Mahalangur Himal in der Ferne dichter Nebel auf the results various! Socioeconomic status im Mahalangur Himal in der Ferne dichter Nebel auf originate from Pakistan, and.! Being very cheap and easily available, it is now commonly used for or... That finally kills his innocence and cardiogenic shocks is only experienced the outcomes of PPD is. Er zu einem der beliebtesten Trekkingziele im Khumbu gehört Inam Khan m, Inam Khan m, Khan. ) male patients were maintained on controlled mechanical ventilation was required for 50 % ) of our patients lived rural! Opinion of domain experts is weighted appreciably more than that of non-specialists contest were awarded cash prizes Tuesday... Very rapidly over the last five decades [ 1 ] been described [ 11 ] all have., fast and hassle-free these governments [ 5,13 ] it easy to be as. ) case Bergwanderer: der trek zum berühmtesten Basislager der Welt the United Kingdom [ ]. With O2 saturation above 95 % more specifically, hair-dye poisoning is emerging as a common component hair-dyes! Common method of suicide, especially in the younger population via urine renal co-morbidities were included in study! In one ( 12.5 % of the poisonings being suicidal in nature ( 75 ). And have banned its use in hair-dyes in Japan, Pakistan, and India ( SPSS Statistics Chicago.
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